Stars Are Not in Outer Space: Astrocytes Respond to Environmental Cues.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 30682369.
- Also identified by DOI 10.1016/j.cell.2018.12.025.
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Abstract
By in vivo screening in zebrafish larvae, Wheeler et al. identify environmental agents that directly modulate transcriptional programs of astrocytes. The herbicide linuron exploits the unfolded protein response pathway to induce a pro-inflammatory program in reactive astrocytes that potentiates inflammatory tissue damage in the CNS.
Medical subject headings
- Astrocytes
- Cues