Response to comment on 'Palovarotene reduces heterotopic ossification in juvenile FOP mice but exhibits pronounced skeletal toxicity'.
Where this comes from
- Record sourced from PubMed, PMID 30698142.
- Also identified by DOI 10.7554/eLife.43928 and PMC identifier 6353591.
- Licence recorded as CC BY.
- The licence permits redistribution, so the abstract is shown in full and the full text is available from the publisher.
Abstract
We respond to concerns expressed by Pacifici and Shore (2019) about a recent paper (Lees-Shepard and Goldhamer, 2018a) in which we reported that the drug palovarotene can have severe side effects in a mouse model of fibrodysplasia ossificans progressiva.
Medical subject headings
- Myositis Ossificans
- Ossification, Heterotopic
- Stilbenes