Intensive Care Admissions and Associated Severity of Influenza B Versus A During Influenza B Vaccine-mismatched Seasons.

Korem, Maya; Orenbuch-Harroch, Efrat; Ben-Chetrit, Eli; Israel, Sarah; Cohen, Matan J; Sviri, Sigal; Levin, Phillip D; Mandelboim, Michal et al. · Clin Infect Dis · 2019

retrospective_cohort · Level III

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Abstract

Patients admitted to hospital with influenza B and A in Jerusalem, Israel, during the 2015-2016 and 2017-2018 influenza seasons demonstrated similar rates of intensive care unit (ICU) admission and associated disease severity. Most (63%) influenza B ICU patients received influenza B-mismatched trivalent vaccine. These findings call into question the equivalence of trivalent and quadrivalent vaccines in preventing severe influenza B.

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