Resistance gene cloning from a wild crop relative by sequence capture and association genetics.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 30718880.
- Also identified by DOI 10.1038/s41587-018-0007-9.
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Abstract
Disease resistance (R) genes from wild relatives could be used to engineer broad-spectrum resistance in domesticated crops. We combined association genetics with R gene enrichment sequencing (AgRenSeq) to exploit pan-genome variation in wild diploid wheat and rapidly clone four stem rust resistance genes. AgRenSeq enables R gene cloning in any crop that has a diverse germplasm panel.
Medical subject headings
- Cloning, Molecular
- Crops, Agricultural
- Disease Resistance
- Genes, Plant
- Plant Diseases