G4Hunter web application: a web server for G-quadruplex prediction.
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- Record sourced from PubMed, PMID 30721922.
- Also identified by DOI 10.1093/bioinformatics/btz087 and PMC identifier 6748775.
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Abstract
Expanding research highlights the importance of guanine quadruplex structures. Therefore, easy-accessible tools for quadruplex analyses in DNA and RNA molecules are important for the scientific community. We developed a web version of the G4Hunter application. This new web-based server is a platform-independent and user-friendly application for quadruplex analyses. It allows retrieval of gene/nucleotide sequence entries from NCBI databases and provides complete characterization of localization and quadruplex propensity of quadruplex-forming sequences. The G4Hunter web application includes an interactive graphical data representation with many useful options including visualization, sorting, data storage and export. G4Hunter web application can be accessed at: http://bioinformatics.ibp.cz. Supplementary data are available at Bioinformatics online.
Medical subject headings
- G-Quadruplexes