Rapid task-dependent tuning of the mouse olfactory bulb.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 30724732.
- Also identified by DOI 10.7554/eLife.43558 and PMC identifier 6365054.
- Licence recorded as CC BY.
- The licence permits redistribution, so the abstract is shown in full and the full text is available from the publisher.
Abstract
Adapting neural representation to rapidly changing behavioural demands is a key challenge for the nervous system. Here, we demonstrate that the output of the primary olfactory area of the mouse, the olfactory bulb, is already a target of dynamic and reproducible modulation. The modulation depends on the stimulus tuning of a given neuron, making olfactory responses more discriminable through selective amplification in a demand-specific way.
Medical subject headings
- Behavior, Animal
- Neurons
- Olfactory Bulb
- Smell