RiboD: a comprehensive database for prokaryotic riboswitches.

Mukherjee, Sumit; Das Mandal, Sukhen; Gupta, Nikita; Drory-Retwitzer, Matan; Barash, Danny; Sengupta, Supratim · Bioinformatics · 2019

basic_science · Level V

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Abstract

Riboswitches are cis-regulatory non-coding genomic segments that control the expression of downstream genes by undergoing conformational change upon ligand binding. We present a comprehensive database of prokaryotic riboswitches that allows the user to search for riboswitches using multiple criteria, extract information about riboswitch location and gene/operon it regulates. RiboD provides a very useful resource that can be utilized for the better understanding of riboswitch-based gene regulation in bacteria and archaea. RiboD can be freely accessed on the web at http://ribod.iiserkol.ac.in/.

Medical subject headings