Chasing the Paradigm: Clinical Translation of 25 Years of Tissue Engineering.

Hoffman, Tyler; Khademhosseini, Ali; Langer, Robert · Tissue Eng Part A · 2019

review · Level V

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Abstract

In this Perspective, we discuss the impact of the past 25 years of tissue engineering on the development of clinical therapies. Based on their success and other significant research accomplishments, platforms of innovation were identified. Their discoveries will enable tissue engineering inspired therapies to meet the requirements necessary for large-scale manufacturing and Food and Drug Administration (FDA) approval for a diverse range of indications.

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