Controlling light in complex media beyond the acoustic diffraction-limit using the acousto-optic transmission matrix.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 30755617.
- Also identified by DOI 10.1038/s41467-019-08583-6 and PMC identifier 6372584.
- Licence recorded as CC BY.
- The licence permits redistribution, so the abstract is shown in full and the full text is available from the publisher.
Abstract
Studying the internal structure of complex samples with light is an important task but a difficult challenge due to light scattering. While the complex optical distortions induced by scattering can be effectively undone if the medium's scattering-matrix is known, this matrix generally cannot be retrieved without the presence of an invasive detector or guide-star at the target points of interest. To overcome this limitation, the current state-of-the-art approaches utilize focused ultrasound for generating acousto-optic guide-stars, in a variety of different techniques. Here, we introduce the acousto-optic transmission matrix (AOTM), which is an ultrasonically-encoded, spatially-resolved, optical scattering-matrix. The AOTM provides both a generalized framework to describe any acousto-optic based technique, and a tool for light control and focusing beyond the acoustic diffraction-limit inside complex samples. We experimentally demonstrate complex light control using the AOTM singular vectors, and utilize the AOTM framework to analyze the resolution limitation of acousto-optic guided focusing approaches.