Extinction dynamics of spiral defect chaos.

Abstract

Spatially extended excitable systems can exhibit spiral defect chaos (SDC) during which spiral waves continuously form and disappear. To address how this dynamical state terminates using simulations can be computationally challenging, especially for large systems. To circumvent this limitation, we treat the number of spiral waves as a stochastic population with a corresponding birth-death equation and use techniques from statistical physics to determine the mean episode duration of SDC. Motivated by cardiac fibrillation, during which the heart's electrical activity becomes disorganized and shows fragmenting spiral waves, we use generic models of cardiac electrophysiology. We show that the duration can be computed in minimal computational time and that it depends exponentially on domain size. Therefore, the approach can result in efficient and accurate predictions of mean episode duration which may be extended to more complex geometries and models.