The glutathione-S-transferase mu-1 null genotype increases wood smoke-induced airway inflammation.

Burbank, Allison J; Vadlamudi, Anusha; Mills, Katherine H; Alt, Ethan M; Wells, Heather; Zhou, Haibo; Alexis, Neil; Hernandez, Michelle L et al. · J Allergy Clin Immunol · 2019

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Abstract

A 2-hour exposure to 500 μg/m<sup>3</sup> wood smoke particles caused neutrophilic airway inflammation in human volunteers, with GSTM1 null genotype being associated with greater inflammatory response to this pollutant.

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