"Deepening" Insight on Skin Aging and Anti-microbial Immunity.

Kobayashi, Tetsuro; Nagao, Keisuke · Cell Metab · 2019

other · Level V

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Abstract

Skin aging is of considerable interest from various perspectives, ranging from aesthetics to cancer development. Zhang et al. (2019) elucidate an immunological consequence of aging in the adipose layer of skin. Age-dependent increases in TGF-β signaling impair fibroblast adipogenic potential that results in impaired anti-bacterial host defense.

Medical subject headings