Mechanism of Action of a New Anti-CD38 Antibody: Enhancing Myeloma Immunotherapy.

Malavasi, Fabio; Faini, Angelo Corso · Clin Cancer Res · 2019

editorial · Level V

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Abstract

Antibody therapy is a treatment option for several diseases, including multiple myeloma. The logic behind it is relatively simple: A target molecule is selected because of its expression on tumor cells, and the antibody delivers cytotoxic effects. Therapeutic results in multiple myeloma indicate that the anti-CD38 antibodies may have relevant immunotherapeutic properties.<i>See related article by Moreno et al., p. 3176</i>.

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