FOXO3, a Molecular Search for the Fountain of Youth.
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 30849363.
- Also identified by DOI 10.1016/j.stem.2019.02.008.
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Abstract
FOXO3 has been consistently associated with longevity and with a reduction in the prevalence of cardiovascular disease. In this issue, Yan et al. (2019) report that FOXO3-activated vascular cells derived from human embryonic stem cells (ESCs) promote multiple vascular functions and reverse cellular aging through the transcriptional repression of CSRP1.
Medical subject headings
- Forkhead Transcription Factors
- Longevity