Will deeper characterization of the landscape of immune checkpoint molecules in acute myeloid leukemia bone marrow lead to improved therapeutic targeting?

Vandsemb, Esten N; Kim, Tae Kon; Zeidan, Amer M · Cancer · 2019

review · Level V

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Abstract

T cells in the bone marrow from patients with acute myeloid leukemia have increased expression of several immune checkpoint molecules. Can this knowledge be translated to novel therapeutic strategies?

Medical subject headings