H3K27M-Positive Primary Spinal Glioblastoma Presenting with Hemorrhage-A Rare Clinical Entity.

Uppar, Alok; Konar, Subhas K; B N, Nandeesh; Shukla, Dhaval · World Neurosurg · 2019

case_report · Level V

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Abstract

Primary spinal glioblastoma multiforme is a rare and aggressive spinal tumor with dismal outcomes CASE DESCRIPTION: We have presented an unusual case-the first, to the best of our knowledge, to be reported-with intratumoral hemorrhage and sudden-onset quadriplegia in a patients with primary spinal glioblastoma multiforme. The patient underwent emergency surgical decompression. The patient died after a prolonged intensive care unit stay. The tumor was positive for histone molecular alteration, H3K27M.

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