Maternal and Infant Bone Mineral Density 1 Year After Delivery in a Randomized, Controlled Trial of Maternal Tenofovir Disoproxil Fumarate to Prevent Mother-to-child Transmission of Hepatitis B Virus.

Salvadori, Nicolas; Fan, Bo; Teeyasoontranon, Waralee; Ngo-Giang-Huong, Nicole; Phanomcheong, Siriluk; Luvira, Anita; Puangsombat, Achara; Suwannarat, Arunrat et al. · Clin Infect Dis · 2019

rct · Level II

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Abstract

In a randomized, double-blind, placebo-controlled trial of tenofovir disoproxil fumarate (TDF) use from 28 weeks gestational age to 2 months postpartum to prevent mother-to-child transmission of hepatitis B virus, there was no significant effect of maternal TDF use on maternal or infant bone mineral density 1 year after delivery/birth. Clinical Trials Registration. NCT01745822.

Medical subject headings