Mast cell recruitment is modulated by the hairless skin microbiome.
Where this comes from
- Record sourced from PubMed, PMID 30928651.
- Also identified by DOI 10.1016/j.jaci.2019.02.033 and PMC identifier 7680643.
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Abstract
Hairless mice have countless mast cells (MCs) in the skin and a more gram positive microbiome (GPM). MC number normalizes when TLR2, a GPM sensor, is deleted, proving a connection between hair-loss, GPM and MCs.
Medical subject headings
- Mast Cells
- Microbiota
- Skin
- Staphylococcus epidermidis