Reoxygenation during radiotherapy in intermediate-risk prostate cancer.

Supiot, Stéphane; Rousseau, Caroline; Dore, Mélanie; Chèze-Le-Rest, Catherine; Kandel-Aznar, Christine; Potiron, Vincent; Guerif, Stéphane; Paris, François et al. · Radiother Oncol · 2019

other · Level V

Where this comes from

Abstract

Hypoxia is a major risk factor of prostate cancer radioresistance. We evaluated hypoxia non-invasively, using <sup>18</sup>F-Misonidazole PET/CT prior to radiotherapy and after a dose of 20 Gy in intermediate-risk prostate cancer patients. Decreased hypoxic volumes were observed in all patients, suggesting that radiotherapy induces early prostate tumor reoxygenation.

Medical subject headings