Fatty Acid Desaturation Gets a NAD<sup>+</sup> Reputation.
editorial · Level V
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- Record sourced from PubMed, PMID 30943390.
- Also identified by DOI 10.1016/j.cmet.2019.03.007 and PMC identifier 7951937.
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Abstract
delta-5 desaturase and delta-6 desaturase are enzymes known to be involved in the synthesis of highly unsaturated fatty acids. In this issue, Kim et al. (2019) show that production of NAD+ by this desaturase reaction is an adaptive response to NAD+ depletion that may regulate cellular REDOX status.
Medical subject headings
- Fatty Acids, Unsaturated
- NAD