RALying Regeneration through Wnt Internalization in Stem Cells.

Tauc, Helen; Jasper, Heinrich · Cell Stem Cell · 2019

editorial · Level V

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Abstract

In this issue of Cell Stem Cell, Johansson et al. (2019) find evolutionarily conserved regulation of Wnt signaling through Ral GTPases. These GTPases promote internalization of Wnt receptor complexes and play a critical role in intestinal stem cell function in flies and mice.

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