Beta Living through Alpha Cells.
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 30951656.
- Also identified by DOI 10.1016/j.stem.2019.03.016.
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Abstract
Recently in Nature, Furuyama et al. (2019) provide evidence for lineage plasticity in the human endocrine pancreas, demonstrating that α cells derived from adult human pancreatic islets can be reprogrammed to become glucose-responsive, insulin-secreting β-like cells that are capable of reversing diabetes in mouse models.
Medical subject headings
- Diabetes Mellitus
- Glucagon-Secreting Cells
- Insulin-Secreting Cells
- Insulins