Counting Calories: The Cost of Inflammation.

Wang, Andrew; Medzhitov, Ruslan · Cell · 2019

basic_science · Level V

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Abstract

A relationship between thermoregulation, metabolism, and the host response to infections has long been appreciated. In this study, Ganeshan and colleagues discover that the immune system regulates body temperature as a strategy to regulate metabolic rate, which in turn promotes tolerance to inflammatory damage.

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