Preemptive Tecovirimat Use in an Active Duty Service Member Who Presented With Acute Myeloid Leukemia After Smallpox Vaccination.
case_report · Level V
Where this comes from
- Record sourced from PubMed, PMID 30959520.
- Also identified by DOI 10.1093/cid/ciz286.
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Abstract
Smallpox vaccine is contraindicated in immunosuppression due to increased risk for adverse reactions (eg, progressive vaccinia). We describe the first-ever use of tecovirimat as a preemptive vaccinia virus treatment strategy during induction chemotherapy in an active duty service member who presented with acute leukemia and inadvertent autoinoculation after smallpox vaccination.
Medical subject headings
- Antiviral Agents
- Benzamides
- Isoindoles
- Leukemia, Myeloid, Acute
- Military Personnel
- Smallpox
- Smallpox Vaccine
- Vaccination
- Vaccinia virus