Subretinal Transplant of Induced Pluripotent Stem Cell-Derived Retinal Pigment Epithelium on Nanostructured Fibrin-Agarose.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 30963803.
- Also identified by DOI 10.1089/ten.TEA.2019.0007.
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Abstract
In the promising field of cellular therapy for retinal degenerative diseases, a new biomaterial is proposed as a scaffold to grow and surgically introduce a monolayer of retinal pigment epithelial cells into the subretinal space, keeping the orientation of the cells for a proper functional integration of the transplant. The use of induced pluripotent stem cells as the starting material for retinal pigment epithelial cells is intended to advance toward a personalized medicine approach.
Medical subject headings
- Induced Pluripotent Stem Cells
- Macular Degeneration
- Monocytes
- Retinal Pigment Epithelium