Hepatitis B Virus and HIV Coinfection: Fibrosis, Fat, and Future Directions.
case_series · Level IV
Where this comes from
- Record sourced from PubMed, PMID 30985299.
- Also identified by DOI 10.14309/ajg.0000000000000231.
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Abstract
HIV and hepatitis B virus (HBV) share routes of transmission, and coinfection is associated with higher levels of HBV DNA, accelerated fibrosis progression, and increased liver-related events compared with those with HBV alone. The full spectrum of hepatic histology has not been recently addressed, in part because of the decreasing use of liver biopsy in clinical practice. The current study provides a modern "snapshot" of biopsy data from 114 HIV/HBV coinfected individuals, elucidating the degree of liver fibrosis years into the effective antiretroviral era and also revealing that hepatic steatosis was a frequent finding.
Medical subject headings
- Coinfection
- HIV Infections