"Cloaking" on Time: A Cover-Up Act by Resident Tissue Macrophages.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 31002790.
- Also identified by DOI 10.1016/j.cell.2019.03.042.
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Abstract
In this issue of Cell, Uderhardt et al. employed intravital two-photon microscopy to examine tissue-resident macrophage responses to sterile cellular injuries of variable size. They observed that while multi-cell "macrolesions" are characteristically pro-inflammatory, resident macrophages can "cloak" single-cell microlesions to prevent excessive neutrophil recruitment and limit subsequent tissue damage.
Medical subject headings
- Macrophages
- Neutrophils