Adjuvant haploidentical virus-specific T lymphocytes for treatment of disseminated adenovirus infection in a premature infant.
case_report · Level V
Where this comes from
- Record sourced from PubMed, PMID 31026470.
- Also identified by DOI 10.1016/j.jaci.2019.04.006 and PMC identifier 6688973.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
We report the first therapeutic infusion of haploidentical virus-specific T lymphocytes (VSTs) to treat maternally-transmitted, disseminated adenovirus infection in a premature infant. Infusion of maternal VSTs, isolated using interferon-gamma capture, associated with clinical improvement and viral clearance.
Medical subject headings
- Adenoviridae Infections
- Adoptive Transfer
- Infant, Newborn, Diseases
- T-Lymphocytes