Evidence for an IL-6-high asthma phenotype in asthmatic patients of African ancestry.

White, Steven R; Laxman, Bharathi; Naureckas, Edward T; Hogarth, D Kyle; Solway, Julian; Sperling, Anne I; Ober, Carole · J Allergy Clin Immunol · 2019

Level IV

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Abstract

High circulating IL-6 may define a phenotype of asthma associated with obesity and systemic inflammation. We demonstrate that circulating IL-6 is higher in African-American patients with asthma, and that race-specific thresholds should be considered.

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