Off-label use of ketamine for treatment-resistant depression in clinical practice: European perspective.

López-Díaz, Álvaro; Murillo-Izquierdo, Manuel; Moreno-Mellado, Elisa · Br J Psychiatry · 2019

editorial · Level V

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Abstract

Ketamine therapy for treatment-resistant depression in European national health systems may only be considered after attempting all evidence-based antidepressant strategies outlined in clinical guidelines. This paper seeks to explain the ethical, regulatory and procedural framework for the off-label use of ketamine for treatment-resistant depression within a public healthcare system.Declaration of interestNone.

Medical subject headings