<i>BRCA</i> Mutation Carriers: Breast and Ovarian Cancer Screening Guidelines and Imaging Considerations.

Elezaby, Mai; Lees, Brittany; Maturen, Katherine E; Barroilhet, Lisa; Wisinski, Kari B; Schrager, Sarina; Wilke, Lee G; Sadowski, Elizabeth · Radiology · 2019

review · Level V

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Abstract

Patients who carry the <i>BRCA</i>1 and <i>BRCA</i>2 gene mutations have an underlying genetic predisposition for breast and ovarian cancers. These deleterious genetic mutations are the most common genes implicated in hereditary breast and ovarian cancers. This monograph summarizes the evidence behind current screening recommendations, reviews imaging protocols specific to this patient population, and illustrates some of the imaging nuances of breast and ovarian cancers in this clinical setting.

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