Increased household exposure to respiratory pathogens in HIV exposed uninfected children due to maternal HIV.

Khan, Tila; Das, Ranjan S; Bhattacharya, Sangeeta D · J Family Med Prim Care · 2019

case_series · Level IV

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Abstract

Little is known about household exposures to respiratory pathogens in HIV-exposed uninfected children (HEU) in Indian families. This case series investigates the nasopharyngeal carriage of <i>Streptococcus pneumoniae</i>, <i>Staphylococcus aureus</i>, and respiratory viruses at multiple points in three mother child pairs: (1) an HIV-infected child and mother, (2) an HEU child and HIV-infected mother, and (3) an HIV-unexposed uninfected (HUU) child and mother. Nasopharyngeal carriage densities of <i>Streptococcus pneumoniae</i> and <i>Staphylococcus aureus</i> were higher in mothers and children living in HIV-affected households, regardless of the child's HIV status. Maternal HIV and ART status impact these household exposures.