Diffuse Uveal Melanocytic Proliferation With Primary Vitreoretinal Lymphoma.

Leskov, Ilya; Lyon, Alice T; Jampol, Lee M · JAMA Ophthalmol · 2019

case_report · Level V

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Abstract

Bilateral diffuse uveal melanocytic proliferation is a rare sign of several systemic malignant neoplasms. A patient presenting with uveal melanocytic proliferation underwent a detailed physical examination and extensive imaging. No systemic malignant neoplasm was found. Chorioretinal biopsy was performed, and its immunohistochemical results revealed the presence of primary vitreoretinal lymphoma. This patient's results suggest that diffuse uveal melanocytic proliferation may be associated not just with systemic malignant disease, but also with primary intraocular tumors, in this case a primary vitreoretinal lymphoma.

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