Nuclear (Bio)physics in the Embryo.

Shvartsman, Stanislav Y; Krajnc, Matej · Cell · 2019

basic_science · Level V

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Abstract

Deneke et al. (2019) discover that dynamic interactions of cell cycle and actomyosin contractility systems synchronize nuclear cleavages, generating a cytoplasmic flow that results in a spatially uniform distribution of zygotic nuclei in the early Drosophila embryo. This work underscores the importance of self-organizing mechanisms before the onset of zygotic transcription.

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