Ancestry Tracing: Uncovering a Gliomagenesis Master Regulator.
editorial · Level V
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- Record sourced from PubMed, PMID 31051128.
- Also identified by DOI 10.1016/j.stem.2019.04.006.
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Abstract
In this issue of Cell Stem Cell, Weng et al. (2019) characterize a progenitor population that precedes oligodendrocyte progenitor cells (OPCs). The authors identified Zfp36l1 as a key regulator of the cell fate switch between oligodendrocytes and astrocytes in neural progenitors, and thereby an important regulator of cellular processes such as myelination and gliomagenesis.
Medical subject headings
- Oligodendrocyte Precursor Cells
- Transcriptome