Airway Histopathology of Adolescent Survivors of Bronchopulmonary Dysplasia.

Galderisi, Alfonso; Calabrese, Fiorella; Fortarezza, Francesco; Abman, Steve; Baraldi, Eugenio · J Pediatr · 2019

case_series · Level IV

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Abstract

Long-term survivors of bronchopulmonary dysplasia develop chronic obstructive lung disease. Herein we report in vivo histopathology from bronchial biopsies of 3 adolescent survivors of severe bronchopulmonary dysplasia. Thickened basement membranes with lymphocytic infiltrates and signs of immature neoangiogenesis in the absence of T-helper lymphocytes or eosinophils suggest the presence of an ongoing active airway process.

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