In vitro biological response of cancer and normal tissue cells to proton irradiation not affected by an added magnetic field.

Nagle, Peter W; van Goethem, Marc-Jan; Kempers, Marco; Kiewit, Harry; Knopf, Antje; Langendijk, Johannes A; Brandenburg, Sytze; van Luijk, Peter et al. · Radiother Oncol · 2019

basic_science · Level V

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Abstract

To optimize beam delivery and conformality of proton therapy, MRI integration has been proposed. Therefore, we investigated if proton irradiation in a magnetic field would change biological responses. Our data in cancer cell lines and stem cell-derived organoid models suggest that a magnetic field does not modify the biological response.

Medical subject headings