Kaposi Sarcoma Herpesvirus Inflammatory Cytokine Syndrome-like Clinical Presentation in Human Immunodeficiency Virus-infected Children in Malawi.
case_series · Level IV
Where this comes from
- Record sourced from PubMed, PMID 31102440.
- Also identified by DOI 10.1093/cid/ciz250 and PMC identifier 6853646.
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Abstract
We describe 7 human immunodeficiency virus-infected Malawian children with Kaposi sarcoma who met criteria for Kaposi sarcoma herpesvirus (KSHV) inflammatory cytokine syndrome. Each presented with persistent fevers, bulky lymphadenopathy, massive hepatosplenomegaly, and severe cytopenias. Plasma analyses were performed in 2 patients, both demonstrating extreme elevations of KSHV viral load and interleukin 6.
Medical subject headings
- Cytokines
- Herpesvirus 8, Human
- Sarcoma, Kaposi