Combined immunodeficiency in a patient with c-Rel deficiency.

Beaussant-Cohen, Sarah; Jaber, Faris; Massaad, Michel J; Weeks, Sabrina; Jones, Jennifer; Alosaimi, Mohammed F; Wallace, Jacqueline; Al-Herz, Waleed et al. · J Allergy Clin Immunol · 2019

case_report · Level V

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Abstract

This study reports a homozygous mutation in <i>REL</i> abrogating c-Rel protein expression in a patient with combined immunodeficiency characterized by susceptibility to <i>Mycobacterium tuberculosis</i>, <i>Salmonella</i>, <i>Cryptosporidium</i>, and cytomegalovirus.

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