Cases in Precision Medicine: The Role of Pharmacogenetics in Precision Prescribing.

Lin, Bohan; Chung, Wendy K · Ann Intern Med · 2019

case_report · Level V

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Abstract

Pharmacogenetics may help physicians deliver individualized treatments based on how a person's genes affect a drug's effects and metabolism. This information can help prevent adverse events or improve drug efficacy by enabling the physician to optimize dosage or to avoid a medication with adverse reactions and to prescribe an alternative therapy. This article discusses the current clinical utility of pharmacogenetic testing in the context of a patient who requires anticoagulation with warfarin.

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