The attempt of spontaneous repair of rotator cuff tear: The role of periostin.
case_series · Level IV
Where this comes from
- Record sourced from PubMed, PMID 31110403.
- Also identified by DOI 10.1016/j.jor.2019.04.018 and PMC identifier 6512582.
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Abstract
The development of a periostin-rich microenvironment in areas associated with insult, orchestrating pathways of repair and rebuilding, is documented. Literature lacks information regarding the presence of periostin in the context of rotator cuff tear (RCT). 55 consecutive patients with RCT were enrolled. Immunohistochemical periostin detection was performed on tissue samples excised from tear margins. Our study documented the presence of periostin in the margins of RCT. It is plausible that, when a tear occurs, multiple stimuli, both mechanical and inflammatory, lead to the development of a periostin-rich microenvironment as an attempt to tendon healing.
Anatomy
- shoulder