SPar-K: a method to partition NGS signal data.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 31116370.
- Also identified by DOI 10.1093/bioinformatics/btz416.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
We present SPar-K (Signal Partitioning with K-means), a method to search for archetypical chromatin architectures by partitioning a set of genomic regions characterized by chromatin signal profiles around ChIP-seq peaks and other kinds of functional sites. This method efficiently deals with problems of data heterogeneity, limited misalignment of anchor points and unknown orientation of asymmetric patterns. SPar-K is a C++ program available on GitHub https://github.com/romaingroux/SPar-K and Docker Hub https://hub.docker.com/r/rgroux/spar-k. Supplementary data are available at Bioinformatics online.
Medical subject headings
- Software