Hemophagocytic lymphohistiocytosis as a diagnostic consideration of fever of unknown origin with pancytopenia and chronic liver disease.
case_report · Level V
Where this comes from
- Record sourced from PubMed, PMID 31143751.
- Also identified by DOI 10.4103/jfmpc.jfmpc_190_19 and PMC identifier 6510086.
- Licence recorded as CC BY-NC-SA.
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Abstract
Hemophagocytic lymphohistiocytosis (HLH) is a severe disorder of systemic immune dysregulation which can be primary or secondary to autoimmune disorders, malignancy, or infections. We hereby describe a case of a 23-year-old male with severe hepatitis along with pancytopenia and prolonged fever of unknown origin that developed HLH triggered by staphylococcal urinary tract infection. This is a discussion of this unusual disease and its presentation and the diagnostic difficulties which may be encountered in general clinical practice.