Chipping Away at Blood-Brain-Barrier Modeling.
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 31173708.
- Also identified by DOI 10.1016/j.stem.2019.05.014.
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Abstract
In this issue, Vatine et al. (2019) present a fully human blood-brain barrier chip that accurately predicts drug permeability and can be perfused with whole blood. Utilizing patient-derived tissue, they recapitulate disease-specific defects and establish a platform to advance drug screening and disease modeling.
Medical subject headings
- Blood-Brain Barrier
- Precision Medicine