Breakthrough Moments: Yoshiki Sasai's Discoveries in the Third Dimension.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 31173711.
- Also identified by DOI 10.1016/j.stem.2019.05.007 and PMC identifier 7085937.
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Abstract
Yoshiki Sasai pioneered the organoid field with his idea of mimicking embryonic development in 3D. We shine a spotlight on his seminal work describing how the innate ability of embryonic stem cells to self-organize into layers and grow in a polarized fashion fosters their appropriate differentiation and response to morphogens.
Medical subject headings
- Brain
- Organoids