Breakthrough Moments: Genome Editing and Organoids.
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 31173713.
- Also identified by DOI 10.1016/j.stem.2019.05.008.
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Abstract
Six years ago, Schwank et al. (2013) adapted CRISPR-Cas9 and organoid technology to repair genetic diseases in patient-derived tissues. We shine a spotlight on how this work has inspired the development of tools to study and correct genetic diseases in experimental systems, with the ultimate goal of treating human disease.
Medical subject headings
- Gene Editing
- Genetic Diseases, Inborn
- Genetic Therapy
- Organoids