Tissue-Engineering the Intestine: The Trials before the Trials.

Clevers, Hans; Conder, Ryan K; Li, Vivian S W; Lutolf, Matthias P; Vallier, Ludovic; Chan, Sarah; Grikscheit, Tracy C; Jensen, Kim B et al. · Cell Stem Cell · 2019

expert_opinion · Level V

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Abstract

Building complex tissues requires the development of innovative interdisciplinary engineering solutions. In this Forum, the INTENS Consortium discuss experimental considerations and challenges for generating a tissue-engineered intestine for the treatment of short bowel syndrome, taking into account cell source, scaffold choice, and design strategy for achieving proper assembly and function.

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