Spatial and episodic memory tasks promote temporal lobe interictal spikes.
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Where this comes from
- Record sourced from PubMed, PMID 31177577.
- Also identified by DOI 10.1002/ana.25519 and PMC identifier 6771851.
- Licence recorded as CC BY.
- The licence permits redistribution, so the abstract is shown in full and the full text is available from the publisher.
Abstract
Reflex epilepsies have been demonstrated to exploit specific networks that subserve normal physiological function. It is unclear whether more common forms of epilepsy share this particular feature. By measuring interictal spikes in patients with a range of epilepsies, we show that 2 tasks known to specifically engage the hippocampus and temporal neocortex promoted increased interictal spiking within these regions, whereas a nonhippocampal dependent task did not. This indicates that interictal spike frequency may reflect the processing demands being placed on specific functional-anatomical networks in epilepsy. ANN NEUROL 2019;86:304-309.
Medical subject headings
- Action Potentials
- Electroencephalography
- Epilepsy, Temporal Lobe
- Memory, Episodic
- Spatial Memory