A comprehensive review of randomized clinical trials in three medical journals reveals 396 medical reversals.
systematic_review · Level I
Where this comes from
- Record sourced from PubMed, PMID 31182188.
- Also identified by DOI 10.7554/eLife.45183 and PMC identifier 6559784.
- Licence recorded as CC BY.
- The licence permits redistribution, so the abstract is shown in full and the full text is available from the publisher.
Abstract
The ability to identify medical reversals and other low-value medical practices is an essential prerequisite for efforts to reduce spending on such practices. Through an analysis of more than 3000 randomized controlled trials (RCTs) published in three leading medical journals (the Journal of the American Medical Association, the Lancet, and the New England Journal of Medicine), we have identified 396 medical reversals. Most of the studies (92%) were conducted on populations in high-income counties, cardiovascular disease was the most common medical category (20%), and medication was the most common type of intervention (33%).
Medical subject headings
- Outcome Assessment, Health Care
- Periodicals as Topic
- Randomized Controlled Trials as Topic
- Research Design