Gastroenteritis, Hepatitis, Encephalopathy, and Human Herpesvirus 6 Detection in an Immunocompetent Child: Benefits and Risks of Syndromic Multiplex Molecular Panel Testing.
case_report · Level V
Where this comes from
- Record sourced from PubMed, PMID 31208781.
- Also identified by DOI 10.1016/j.jpeds.2019.04.058 and PMC identifier 6707859.
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Abstract
An immunocompetent toddler came to medication attention with gastroenteritis, complicated by encephalopathy and hepatitis. Multiplexed testing using a polymerase chain reaction meningitis panel was positive for human herpesvirus 6 (HHV-6). Clinical correlation, quantitative HHV-6 polymerase chain reaction, and metagenomic next-generation sequencing supported a likely diagnosis of primary HHV-6B infection.
Medical subject headings
- Brain Diseases
- Exanthema Subitum
- Gastroenteritis
- Hepatitis
- Herpesvirus 6, Human
- Multiplex Polymerase Chain Reaction